Diacylglycerol kinase zeta negatively regulates CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow.

Lee D, Kim J, Beste MT, Koretzky GA, Hammer DA.

Integr Biol (Camb). 2012 May 1. [Epub ahead of print]

PMID:
22546945
[PubMed - as supplied by publisher]

Immunoinformatics: how in silico methods are re-shaping the investigation of peptide immune specificity.

Wee LJ, Lim SJ, Ng LF, Tong JC.

Front Biosci (Elite Ed). 2012 Jan 1;4:311-9. Review.

PMID:
22201873
[PubMed - indexed for MEDLINE]

Virus replication strategies and the critical CTL numbers required for the control of infection.

Yates AJ, Van Baalen M, Antia R.

PLoS Comput Biol. 2011 Nov;7(11):e1002274. Epub 2011 Nov 17.

PMID:
22125483
[PubMed - indexed for MEDLINE]

Free PMC Article

Systemic remodeling of the redox regulatory network due to RNAi perturbations of glutaredoxin 1, thioredoxin 1, and glucose-6-phosphate dehydrogenase.

Kippner LE, Finn NA, Shukla S, Kemp ML.

BMC Syst Biol. 2011 Oct 13;5:164.

PMID:
21995976
[PubMed - indexed for MEDLINE]

Free PMC Article

Modeling of influenza-specific CD8+ T cells during the primary response indicates that the spleen is a major source of effectors.

Wu H, Kumar A, Miao H, Holden-Wiltse J, Mosmann TR, Livingstone AM, Belz GT, Perelson AS, Zand MS, Topham DJ.

J Immunol. 2011 Nov 1;187(9):4474-82. Epub 2011 Sep 23.

PMID:
21948988
[PubMed - indexed for MEDLINE]

Implicit methods for qualitative modeling of gene regulatory networks.

Garg A, Mohanram K, De Micheli G, Xenarios I.

Methods Mol Biol. 2012;786:397-443.

PMID:
21938638
[PubMed - indexed for MEDLINE]

Discovery of novel promising targets for anti-AIDS drug developments by computer modeling: application to the HIV-1 gp120 V3 loop.

Andrianov AM, Anishchenko IV, Tuzikov AV.

J Chem Inf Model. 2011 Oct 24;51(10):2760-7. Epub 2011 Sep 22.

PMID:
21888425
[PubMed - indexed for MEDLINE]

Systems biology approaches for understanding cellular mechanisms of immunity in lymph nodes during infection.

Mirsky HP, Miller MJ, Linderman JJ, Kirschner DE.

J Theor Biol. 2011 Oct 21;287:160-70. Epub 2011 Jul 23. Review.

PMID:
21798267
[PubMed - indexed for MEDLINE]

Modeling the effector – regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis.

Vélez de Mendizábal N, Carneiro J, Solé RV, Goñi J, Bragard J, Martinez-Forero I, Martinez-Pasamar S, Sepulcre J, Torrealdea J, Bagnato F, Garcia-Ojalvo J, Villoslada P.

BMC Syst Biol. 2011 Jul 15;5:114.

PMID:
21762505
[PubMed - indexed for MEDLINE]

Free PMC Article

An in silico modeling approach to understanding the dynamics of sarcoidosis.

Aguda BD, Marsh CB, Thacker M, Crouser ED.

PLoS One. 2011;6(5):e19544. Epub 2011 May 27.

PMID:
21637752
[PubMed - indexed for MEDLINE]

Free PMC Article

Characterization of structural features controlling the receptiveness of empty class II MHC molecules.

Rupp B, Günther S, Makhmoor T, Schlundt A, Dickhaut K, Gupta S, Choudhary I, Wiesmüller KH, Jung G, Freund C, Falk K, Rötzschke O, Kühne R.

PLoS One. 2011 Apr 14;6(4):e18662.

PMID:
21533180
[PubMed - indexed for MEDLINE]

Free PMC Article

Large-scale characterization of peptide-MHC binding landscapes with structural simulations.

Yanover C, Bradley P.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6981-6. Epub 2011 Apr 8.

PMID:
21478437
[PubMed - indexed for MEDLINE]

Free PMC Article

Combining network modeling and gene expression microarray analysis to explore the dynamics of Th1 and Th2 cell regulation.

Pedicini M, Barrenäs F, Clancy T, Castiglione F, Hovig E, Kanduri K, Santoni D, Benson M.

PLoS Comput Biol. 2010 Dec 16;6(12):e1001032.

PMID:
21187905
[PubMed - indexed for MEDLINE]

Free PMC Article

Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response.

Feinerman O, Jentsch G, Tkach KE, Coward JW, Hathorn MM, Sneddon MW, Emonet T, Smith KA, Altan-Bonnet G.

Mol Syst Biol. 2010 Nov 30;6:437.

PMID:
21119631
[PubMed - indexed for MEDLINE]

Free PMC Article

On how monospecific memory-like autoregulatory CD8+ T cells can blunt diabetogenic autoimmunity: a computational approach.

Khadra A, Tsai S, Santamaria P, Edelstein-Keshet L.

J Immunol. 2010 Nov 15;185(10):5962-72. Epub 2010 Oct 20.

PMID:
20962260
[PubMed - indexed for MEDLINE]

Free Article

Bcl-2 inhibits apoptosis by increasing the time-to-death and intrinsic cell-to-cell variations in the mitochondrial pathway of cell death.

Skommer J, Brittain T, Raychaudhuri S.

Apoptosis. 2010 Oct;15(10):1223-33.

PMID:
20563668
[PubMed - indexed for MEDLINE]

Free PMC Article

Perspectives for computer modeling in the study of T cell activation.

Coward J, Germain RN, Altan-Bonnet G.

Cold Spring Harb Perspect Biol. 2010 Jun;2(6):a005538. Epub 2010 May 5. Review.

PMID:
20516137
[PubMed - indexed for MEDLINE]

Free PMC Article

The pathogenicity of self-antigen decreases at high levels of autoantigenicity: a computational approach.

Khadra A, Santamaria P, Edelstein-Keshet L.

Int Immunol. 2010 Jul;22(7):571-82. Epub 2010 May 24.

PMID:
20497954
[PubMed - indexed for MEDLINE]

Free PMC Article

Conformational flexibility in designing peptides for immunology: the molecular dynamics approach.

Stavrakoudis A.

Curr Comput Aided Drug Des. 2010 Sep;6(3):207-22. Review.

PMID:
20412039
[PubMed - indexed for MEDLINE]

Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virus.

Miao H, Hollenbaugh JA, Zand MS, Holden-Wiltse J, Mosmann TR, Perelson AS, Wu H, Topham DJ.

J Virol. 2010 Jul;84(13):6687-98. Epub 2010 Apr 21.

PMID:
20410284
[PubMed - indexed for MEDLINE]

Free PMC Article

Modeling and simulation of the immune system as a self-regulating network.

Kim PS, Levy D, Lee PP.

Methods Enzymol. 2009;467:79-109.

PMID:
19897090
[PubMed - indexed for MEDLINE]

Modeling dynamic changes in type 1 diabetes progression: quantifying beta-cell variation after the appearance of islet-specific autoimmune responses.

Nelson P, Smith N, Ciupe S, Zou W, Omenn GS, Pietropaolo M.

Math Biosci Eng. 2009 Oct;6(4):753-78. doi: 10.3934/mbe.2009.6.753.

PMID:
19835428
[PubMed - indexed for MEDLINE]

Immunoinformatics and modeling perspective of T cell epitope-based cancer immunotherapy: a holistic picture.

Mishra S, Sinha S.

J Biomol Struct Dyn. 2009 Dec;27(3):293-306. Review.

PMID:
19795913
[PubMed - indexed for MEDLINE]

Predicting affinity and specificity of antigenic peptide binding to major histocompatibility class I molecules.

Sieker F, May A, Zacharias M.

Curr Protein Pept Sci. 2009 Jun;10(3):286-96. Review.

PMID:
19519456
[PubMed - indexed for MEDLINE]

Parallel multi-time point cell stimulation and lysis on-chip for studying early signaling events in T cell activation.

Hirsch AM, Rivet CA, Zhang B, Kemp ML, Lu H.

Lab Chip. 2009 Feb 21;9(4):536-44. Epub 2008 Nov 20.

PMID:
19190789
[PubMed - indexed for MEDLINE]

Characterizing emergent properties of immunological systems with multi-cellular rule-based computational modeling.

Chavali AK, Gianchandani EP, Tung KS, Lawrence MB, Peirce SM, Papin JA.

Trends Immunol. 2008 Dec;29(12):589-99. Epub 2008 Oct 27. Review.

PMID:
18964301
[PubMed - indexed for MEDLINE]

Variability and robustness in T cell activation from regulated heterogeneity in protein levels.

Feinerman O, Veiga J, Dorfman JR, Germain RN, Altan-Bonnet G.

Science. 2008 Aug 22;321(5892):1081-4.

PMID:
18719282
[PubMed - indexed for MEDLINE]

Free PMC Article

Detection of interferon gamma-secreting CD8+ T lymphocytes in humans specific for three PE/PPE proteins of Mycobacterium tuberculosis.

Chaitra MG, Shaila MS, Nayak R.

Microbes Infect. 2008 Jul;10(8):858-67. Epub 2008 May 2.

PMID:
18653370
[PubMed - indexed for MEDLINE]

Modeling and estimation of kinetic parameters and replicative fitness of HIV-1 from flow-cytometry-based growth competition experiments.

Miao H, Dykes C, Demeter LM, Cavenaugh J, Park SY, Perelson AS, Wu H.

Bull Math Biol. 2008 Aug;70(6):1749-71. Epub 2008 Jul 22.

PMID:
18648886
[PubMed - indexed for MEDLINE]

Grouping of class I HLA alleles using electrostatic distribution maps of the peptide binding grooves.

Kangueane P, Sakharkar MK.

Methods Mol Biol. 2007;409:175-81.

PMID:
18450000
[PubMed - indexed for MEDLINE]

Retractile processes in T lymphocyte orientation on a stimulatory substrate: morphology and dynamics.

Arkhipov SN, Maly IV.

Phys Biol. 2008 Apr 1;5(1):016006.

PMID:
18379018
[PubMed - indexed for MEDLINE]

Free PMC Article

TWIK-related acid-sensitive K+ channel 1 (TASK1) and TASK3 critically influence T lymphocyte effector functions.

Meuth SG, Bittner S, Meuth P, Simon OJ, Budde T, Wiendl H.

J Biol Chem. 2008 May 23;283(21):14559-70. Epub 2008 Mar 28.

PMID:
18375952
[PubMed - indexed for MEDLINE]

Free Article

Immune selection during chronic hepadnavirus infection.

Mason WS, Litwin S, Jilbert AR.

Hepatol Int. 2008 Mar;2(1):3-16. Epub 2007 Dec 14.

PMID:
19669275
[PubMed]

Free PMC Article

The neoplastically transformed (CD30hi) Marek’s disease lymphoma cell phenotype most closely resembles T-regulatory cells.

Shack LA, Buza JJ, Burgess SC.

Cancer Immunol Immunother. 2008 Aug;57(8):1253-62. Epub 2008 Feb 7.

PMID:
18256827
[PubMed - indexed for MEDLINE]

A statistical framework for modeling HLA-dependent T cell response data.

Listgarten J, Frahm N, Kadie C, Brander C, Heckerman D.

PLoS Comput Biol. 2007 Oct;3(10):1879-86.

PMID:
17937494
[PubMed - indexed for MEDLINE]

Free PMC Article

A logical model provides insights into T cell receptor signaling.

Saez-Rodriguez J, Simeoni L, Lindquist JA, Hemenway R, Bommhardt U, Arndt B, Haus UU, Weismantel R, Gilles ED, Klamt S, Schraven B.

PLoS Comput Biol. 2007 Aug;3(8):e163. Epub 2007 Jul 5.

PMID:
17722974
[PubMed - indexed for MEDLINE]

Free PMC Article

A model for the interplay of receptor recycling and receptor-mediated contact in T cells.

Arkhipov SN, Maly IV.

PLoS One. 2007 Jul 25;2(7):e633.

PMID:
17653260
[PubMed - indexed for MEDLINE]

Free PMC Article

HIV integration site selection: analysis by massively parallel pyrosequencing reveals association with epigenetic modifications.

Wang GP, Ciuffi A, Leipzig J, Berry CC, Bushman FD.

Genome Res. 2007 Aug;17(8):1186-94. Epub 2007 Jun 1.

PMID:
17545577
[PubMed - indexed for MEDLINE]

Free PMC Article

Electrostatic modeling of peptides derived from the V3-loop of HIV-1 gp120: implications of the interaction with chemokine receptor CCR5.

Morikis D, Rizos AK, Spandidos DA, Krambovitis E.

Int J Mol Med. 2007 Mar;19(3):343-51.

PMID:
17273779
[PubMed - indexed for MEDLINE]

Pharmacodynamics of antiretroviral agents in HIV-1 infected patients: using viral dynamic models that incorporate drug susceptibility and adherence.

Wu H, Huang Y, Acosta EP, Park JG, Yu S, Rosenkranz SL, Kuritzkes DR, Eron JJ, Perelson AS, Gerber JG.

J Pharmacokinet Pharmacodyn. 2006 Aug;33(4):399-419. Epub 2006 Apr 1.

PMID:
16583266
[PubMed - indexed for MEDLINE]

Prediction of HLA-DQ3.2beta ligands: evidence of multiple registers in class II binding peptides.

Tong JC, Zhang GL, Tan TW, August JT, Brusic V, Ranganathan S.

Bioinformatics. 2006 May 15;22(10):1232-8. Epub 2006 Mar 1.

PMID:
16510499
[PubMed - indexed for MEDLINE]

Free Article

A combined immuno-informatics and structure-based modeling approach for prediction of T cell epitopes of secretory proteins of Mycobacterium tuberculosis.

Vani J, Shaila MS, Chandra NR, Nayak R.

Microbes Infect. 2006 Mar;8(3):738-46. Epub 2006 Jan 18.

PMID:
16476561
[PubMed - indexed for MEDLINE]

The folding energy landscape and phosphorylation: modeling the conformational switch of the NFAT regulatory domain.

Shen T, Zong C, Hamelberg D, McCammon JA, Wolynes PG.

FASEB J. 2005 Sep;19(11):1389-95.

PMID:
16126906
[PubMed - indexed for MEDLINE]

Free Article

Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity.

Weinberger LS, Burnett JC, Toettcher JE, Arkin AP, Schaffer DV.

Cell. 2005 Jul 29;122(2):169-82.

PMID:
16051143
[PubMed - indexed for MEDLINE]

Agent-based modeling of the context dependency in T cell recognition.

Casal A, Sumen C, Reddy TE, Alber MS, Lee PP.

J Theor Biol. 2005 Oct 21;236(4):376-91.

PMID:
15899504
[PubMed - indexed for MEDLINE]

Dietary flavonoids as proteasome inhibitors and apoptosis inducers in human leukemia cells.

Chen D, Daniel KG, Chen MS, Kuhn DJ, Landis-Piwowar KR, Dou QP.

Biochem Pharmacol. 2005 May 15;69(10):1421-32.

PMID:
15857606
[PubMed - indexed for MEDLINE]

Immunology and mathematics: crossing the divide.

Callard RE, Yates AJ.

Immunology. 2005 May;115(1):21-33. Review.

PMID:
15819694
[PubMed - indexed for MEDLINE]

Free PMC Article

Quantitating effector and regulatory T lymphocytes in immune responses by limiting dilution analysis modeling.

Bonnefoix T, Bonnefoix P, Perron P, Mi JQ, Ng WF, Lechler R, Bensa JC, Cahn JY, Leroux D.

J Immunol. 2005 Mar 15;174(6):3421-31.

PMID:
15749876
[PubMed - indexed for MEDLINE]

Free Article

A mathematical approach for optimizing dendritic cell-based immunotherapy.

Bocharov G, Ford NJ, Ludewig B.

Methods Mol Med. 2005;109:19-34.

PMID:
15585910
[PubMed - indexed for MEDLINE]

Structure-based discovery of nonpeptidic small organic compounds to block the T cell response to myelin basic protein.

Koehler NK, Yang CY, Varady J, Lu Y, Wu XW, Liu M, Yin D, Bartels M, Xu BY, Roller PP, Long YQ, Li P, Kattah M, Cohn ML, Moran K, Tilley E, Richert JR, Wang S.

J Med Chem. 2004 Oct 7;47(21):4989-97.

PMID:
15456243
[PubMed - indexed for MEDLINE]

Toward rigorous comprehension of biological complexity: modeling, execution, and visualization of thymic T-cell maturation.

Efroni S, Harel D, Cohen IR.

Genome Res. 2003 Nov;13(11):2485-97. Erratum in: Genome Res. 2004 Jan;14(1):197.

PMID:
14597657
[PubMed - indexed for MEDLINE]

Free PMC Article

Bioinformatics of granzymes: sequence comparison and structural studies on granzyme family by homology modeling.

Sattar R, Ali SA, Abbasi A.

Biochem Biophys Res Commun. 2003 Sep 5;308(4):726-35.

PMID:
12927779
[PubMed - indexed for MEDLINE]

Growth factors, cytokines, chemokines and neuropeptides in the modeling of T cells. Part II: Data tables of normal values in man.

Krueger GR, Marshall GR, Junker U, Schroeder H, Buja LM.

In Vivo. 2003 Mar-Apr;17(2):105-18. Review.

PMID:
12792970
[PubMed - indexed for MEDLINE]

Identification and utilization of arbitrary correlations in models of recombination signal sequences.

Cowell LG, Davila M, Kepler TB, Kelsoe G.

Genome Biol. 2002;3(12):RESEARCH0072. Epub 2002 Nov 21.

PMID:
12537561
[PubMed - indexed for MEDLINE]

Free PMC Article

Growth factors, cytokines, chemokines and neuropeptides in the modeling of T-cells.

Krueger GR, Marshall GR, Junker U, Schroeder H, Buja LM, Wang G.

In Vivo. 2002 Sep-Oct;16(5):365-86. Review.

PMID:
12494879
[PubMed - indexed for MEDLINE]

Human genome search in celiac disease: mutated gliadin T-cell-like epitope in two human proteins promotes T-cell activation.

Kumar R, Eastwood AL, Brown ML, Laurie GW.

J Mol Biol. 2002 Jun 7;319(3):593-602.

PMID:
12054857
[PubMed - indexed for MEDLINE]

Predicting sequences and structures of MHC-binding peptides: a computational combinatorial approach.

Zen J, Treutlein HR, Rudy GB.

J Comput Aided Mol Des. 2001 Jun;15(6):573-86.

PMID:
11495228
[PubMed - indexed for MEDLINE]

Modeling the meta-dynamics of lymphocyte repertoires.

Mehr R.

Arch Immunol Ther Exp (Warsz). 2001;49(2):111-20. Review.

PMID:
11348015
[PubMed - indexed for MEDLINE]

A systematic approach to vaccine complexity using an automaton model of the cellular and humoral immune system. I. Viral characteristics and polarized responses.

Kohler B, Puzone R, Seiden PE, Celada F.

Vaccine. 2000 Nov 22;19(7-8):862-76.

PMID:
11115710
[PubMed - indexed for MEDLINE]

A geometric study of the amino acid sequence of class I HLA molecules.

Cano P, Fan B, Stass S.

Immunogenetics. 1998 Oct;48(5):324-34.

PMID:
9745009
[PubMed - indexed for MEDLINE]

     

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